Cell & DNA Repair
Peptides offer several potential benefits for DNA and cell repair, making them a promising option in regenerative medicine and anti-aging therapies:
Enhancement of DNA Repair Mechanisms: Certain peptides, such as GHK-Cu and Epitalon, have been shown to promote DNA repair by upregulating genes related to cellular repair and restoration. GHK-Cu, for example, can reset gene expression patterns to a healthier state and stimulate the expression of DNA repair genes, helping cells recover from damage.
Cellular Regeneration and Anti-Aging: Peptides like GHK-Cu and BPC-157 support tissue remodeling, collagen synthesis, and wound healing. They can also boost mitochondrial function, which is crucial for cellular energy and overall cell health.
Improved Tissue Healing: Injectable peptides can accelerate wound healing, reduce inflammation, and promote the growth of new blood vessels. GHK-Cu, in particular, has demonstrated strong regenerative effects in skin, bone, and other tissues.
Telomere Protection: Peptides such as Epitalon may help lengthen telomeres (the protective ends of chromosomes), which are associated with cellular aging and DNA stability.
Overall, injectable peptides can help maintain cellular integrity, support DNA repair, and promote tissue regeneration, potentially slowing the aging process and improving recovery from injury or cellular damage
Here are some notable peptides and peptide-based compounds associated with DNA and cell repair, based on current research and clinical use:
GHK-Cu (Copper Tripeptide-1): Stimulates DNA repair, tissue remodeling, and collagen synthesis. It is widely used in skin care and regenerative medicine for its ability to reset gene expression to a healthier state and promote cellular repair.
Epitalon: A synthetic peptide derived from the pineal gland that may help protect telomeres, support DNA stability, and promote longevity.
BPC-157: Known for its regenerative effects on tissues, wound healing, and anti-inflammatory properties, though its direct role in DNA repair is less established than its cell repair benefits.
NAD+ (nicotinamide adenine dinucleotide):
It is a vital coenzyme in all cells that plays a crucial role in DNA repair and maintaining genomic stability. Here are its key benefits for DNA repair:
Supports Multiple DNA Repair Pathways: NAD+ is required as a substrate by several DNA repair enzymes, including PARP1, PARP2, and sirtuins, which are involved in base excision repair, double-strand break repair, and other mechanisms.
Enhances Genomic Stability: Adequate NAD+ levels help prevent the accumulation of DNA damage, which is linked to aging and age-related diseases.
Boosts Cellular Resilience to Damage: Supplementing with NAD+ or its precursors (such as NMN and NR) can improve DNA repair efficiency, especially in conditions of accelerated aging or following exposure to DNA-damaging agents.
Reduces Age-Related DNA Damage: Declining NAD+ levels with age are associated with reduced DNA repair capacity; increasing NAD+ can help restore this function and may slow certain effects of aging.
Protects Against Disease: NAD+ supplementation has shown promise in reducing DNA damage and improving outcomes in diseases linked to impaired DNA repair, such as certain neurodegenerative and progeroid syndromes.